Structure of PDB 6lm2 Chain A Binding Site BS01

Receptor Information
>6lm2 Chain A (length=184) Species: 866768 (Escherichia coli 'BL21-Gold(DE3)pLysS AG') [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTEVEQKAANGVFDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKK
ADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHRNNETTSCKYDYD
GYKILTYKSGKKGVRYLFECKDPESKAPKYIQFSDHIIAPRKSSHFHIFM
GNDSQQSLLNEMENWPTYYPKQLSSEEVVEEMMS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6lm2 Chain A Residue 205 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6lm2 Crystal structure of Zinc binding protein ZinT from E. coli
Resolution2.13008 Å
Binding residue
(original residue number in PDB)
H144 H155
Binding residue
(residue number reindexed from 1)
H136 H147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046870 cadmium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006882 intracellular zinc ion homeostasis
GO:0034224 cellular response to zinc ion starvation
GO:0070301 cellular response to hydrogen peroxide
GO:0071276 cellular response to cadmium ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6lm2, PDBe:6lm2, PDBj:6lm2
PDBsum6lm2
PubMed
UniProtP76344|ZINT_ECOLI Metal-binding protein ZinT (Gene Name=zinT)

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