Structure of PDB 6lf6 Chain A Binding Site BS01

Receptor Information
>6lf6 Chain A (length=457) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARPHVVLLPSAGMGHLVPFARLAVALSEGHGCNVSVAAVQPTVSSAESRL
LDALFVAAAPAVRRLDFRLAPFDESEFPGADPFFLRFEATRRSAPLLGPL
LDAAEASALVTDIVLASVALPVARERGVPCYVLFTSSAAMLSLCAYFPAY
LDAHAAAGVGVGNVDIPGFRIPKSSVPQALHDPDHLFTQQFVANGRCLVA
CDGILVNTFDAFEPDAVTALRQGSITVSGGFPPVFTVGPMLPVRFQAEET
ADYMRWLSAQPPRSVVYVSFGSRKAIPRDQLRELAAGLEASGKRFLWVVK
STIVDRDDTADLGGLLGDGFLERVQGRAFVTMGWVEQEEILQHGSVGLFI
SHCGWNSLTEAAAFGVPVLAWPRFGDQRVNAALVARSGLGAWEEGWTWDG
EEGLTTRKEVAKKIKGMMGYDAVAEKAAKVGDAAAAAIAKCGTSYQSLEE
FVQRCRD
Ligand information
Ligand IDUDP
InChIInChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyXCCTYIAWTASOJW-XVFCMESISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
CACTVS 3.370O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
CACTVS 3.370O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
FormulaC9 H14 N2 O12 P2
NameURIDINE-5'-DIPHOSPHATE
ChEMBLCHEMBL130266
DrugBankDB03435
ZINCZINC000004490939
PDB chain6lf6 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lf6 Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Resolution2.044 Å
Binding residue
(original residue number in PDB)		G285 S286 K314 W348 V349 Q351 H366 G368 N370 S371 E374
Binding residue
(residue number reindexed from 1)		G271 S272 K300 W334 V335 Q337 H352 G354 N356 S357 E360
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0035251 UDP-glucosyltransferase activity
GO:0047243 flavanone 7-O-beta-glucosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6lf6, PDBe:6lf6, PDBj:6lf6
PDBsum6lf6
PubMed33199630
UniProtA0A096SRM5|708A6_MAIZE UDP-glycosyltransferase 708A6 (Gene Name=UGT708A6)

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