Structure of PDB 6l86 Chain A Binding Site BS01

Receptor Information
>6l86 Chain A (length=292) Species: 66431 (Streptomyces thioluteus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKAQSGSSFGASVEGFDHTTATAEDIKAIKETIYTKKIAVLKGQDLTP
AQYLELGKMFGRPVVYYEPMYKHPEFEEIFVSSNVPGKQIGVPKTGKFWH
ADYQFMPDPFGLTLIYPQVIPQKNRGTYYIDMGKAYERLPQELKDEVAGL
YGVHSVRKYFKIRPHDVYRPISEILTEIEEHTPPVRQPLTFKHPLTGETV
LYISEGFTVGLEDADGKPVESDLLQRLFEATGQLDDTFTHENIHLFHPEQ
GDLLIWDNRSLIHRALHTTTPEPVVSFRVTVHDEHKLYDGMP
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain6l86 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6l86 Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases.
Resolution2.23 Å
Binding residue
(original residue number in PDB)		H102 D104 H265
Binding residue
(residue number reindexed from 1)		H100 D102 H263
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H102 D104 H265 R280
Catalytic site (residue number reindexed from 1) H100 D102 H263 R278
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6l86, PDBe:6l86, PDBj:6l86
PDBsum6l86
PubMed32074393
UniProtA0A2H4T920

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