Structure of PDB 6l6s Chain A Binding Site BS01

Receptor Information
>6l6s Chain A (length=207) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGE
QPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAA
GGKRRIEKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDF
RVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLR
VAADVRP
Ligand information
Receptor-Ligand Complex Structure
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PDB6l6s Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
Resolution2.06426 Å
Binding residue
(original residue number in PDB)		P68 A69 E109 G140 A141 R153 V154 T155 V177 H178 S180 S181 L183 R184
Binding residue
(residue number reindexed from 1)		P66 A67 E107 G138 A139 R151 V152 T153 V175 H176 S178 S179 L181 R182
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0097506 deaminated base DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6l6s, PDBe:6l6s, PDBj:6l6s
PDBsum6l6s
PubMed33248387
UniProtI7F541

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