Structure of PDB 6ks0 Chain A Binding Site BS01

Receptor Information
>6ks0 Chain A (length=286) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGN
IWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFS
WLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLI
YLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTI
AEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSH
QIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ks0 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ks0 Human adiponectin receptor AdipoR1 assumes closed and open structures.
Resolution2.79 Å
Binding residue
(original residue number in PDB)		H191 H337 H341
Binding residue
(residue number reindexed from 1)		H104 H250 H254
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6ks0, PDBe:6ks0, PDBj:6ks0
PDBsum6ks0
PubMed32796916
UniProtQ96A54|PAQR1_HUMAN Adiponectin receptor protein 1 (Gene Name=ADIPOR1)

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