Structure of PDB 6kpm Chain A Binding Site BS01

Receptor Information
>6kpm Chain A (length=295) Species: 983644 (Cordyceps militaris CM01) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSVCPSDNTHATGAALQKILDYKKGDHQIMAGYFRSWRDTASGTGNKVSM
LDLPDCLDIAFVFPEGDETASFWTTLKDTYVPALHGRGIKVVRSVGIAQL
INTAWDNTPAGWQGLADALMKTVDDYGLDGLDIDVEQSLNANQLKQATGV
FNALAKKLGPKSGTGKLLIFDTNMDGTQPLWRNVYPTISYVLIQSYGRSI
SGLQTTYNSFKSYISSKQYLIGFSFYEENGTNWGDTTTPMTSSRAWQYAK
WQPSGATKGGIFSYAIDRDGVAIGDNTLKTTDFTWTRQLIGAMNP
Ligand information
Ligand IDFUC
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6+/m0/s1
InChIKeySHZGCJCMOBCMKK-SXUWKVJYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O
CACTVS 3.341C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
FormulaC6 H12 O5
Namealpha-L-fucopyranose;
alpha-L-fucose;
6-deoxy-alpha-L-galactopyranose;
L-fucose;
fucose
ChEMBLCHEMBL1232862
DrugBankDB04473
ZINCZINC000001532814
PDB chain6kpm Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6kpm Structural basis for the specific cleavage of core-fucosylatedN-glycans by endo-beta-N-acetylglucosaminidase from the fungusCordyceps militaris.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		N193 Q214 Y216 R218
Binding residue
(residue number reindexed from 1)		N173 Q194 Y196 R198
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.14: chitinase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568 chitinase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6kpm, PDBe:6kpm, PDBj:6kpm
PDBsum6kpm
PubMed31548313
UniProtG3JPF7

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