Structure of PDB 6jwj Chain A Binding Site BS01

Receptor Information

>6jwj Chain A (length=466) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SIKELAVDEELAAADGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEK
NKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPW
PRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFG
YMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQID
RQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARH
QTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTA
DMISGSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVKENAKPAFPVDY
LLVTLTHGFPNTTNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASS
GDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLV
SSAGWQTLVMILQESG

Ligand information

>6jwj Chain C (length=19) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

MEPAKLDLPEGQLFFGFPM

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6jwj Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4.
Resolution	1.58 Å
Binding residue (original residue number in PDB)	Q258 D294 G295 L296 T297 V300 F326 T327 D328 F340 K342 L353 E354 R364 S415 G416 S417 T418 F419 P420 Y424 N426 P455
Binding residue (residue number reindexed from 1)	Q147 D183 G184 L185 T186 V189 F215 T216 D217 F229 K231 L242 E243 R253 S304 G305 S306 T307 F308 P309 Y313 N315 P344

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006511	ubiquitin-dependent protein catabolic process

View graph for
Biological Process

External links

PDB	RCSB:6jwj, PDBe:6jwj, PDBj:6jwj
PDBsum	6jwj
PubMed	31836717
UniProt	P33755\|NPL4_YEAST Nuclear protein localization protein 4 (Gene Name=NPL4)

[Back to BioLiP]