Structure of PDB 6jvw Chain A Binding Site BS01

Receptor Information
>6jvw Chain A (length=260) Species: 627192 (Sphingobium sp. SYK-6) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLARFDGGRLGVVIGDEIADITALTGADPAQWPDMNMIRLIRDFEGLRG
AIEAALPGLARIPLAQVSLETPVPWPNKIIAYPVNYHAGFFLKPGSALSG
PTDPVVLPAVPGREVHHESELAIIIGKTCRSVAREDWKDVVFGYACLLDM
VVRGRVFRKAYDTFCPVGPWITTADAVNDPATLDMKLWVNDDLRQKANTR
DLVLDIPGMIATASAVMTLQPGDIIATGTPEGVGPVVDGDRIRIVIDQVG
EMAVDVVQGQ
Ligand information
Ligand IDPYR
InChIInChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKeyLCTONWCANYUPML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CC(=O)C(O)=O
OpenEye OEToolkits 1.7.6CC(=O)C(=O)O
ACDLabs 12.01O=C(C(=O)O)C
FormulaC3 H4 O3
NamePYRUVIC ACID
ChEMBLCHEMBL1162144
DrugBankDB00119
ZINCZINC000001532517
PDB chain6jvw Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jvw Structural insights into a maleylpyruvate hydrolase from sphingobium sp. SYK-6, a bacterium degrading lignin-derived aryls.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		P83 V84 F105 E132 K176
Binding residue
(residue number reindexed from 1)		P83 V84 F91 E118 K159
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0018773 acetylpyruvate hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6jvw, PDBe:6jvw, PDBj:6jvw
PDBsum6jvw
PubMed31079929
UniProtG2IPX5

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