Structure of PDB 6jtd Chain A Binding Site BS01

Receptor Information
>6jtd Chain A (length=477) Species: 78479 (Trollius chinensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPNSTSKPHVFLLASPGMGHLIPFLELSKRLVTLNTLQVTLFIVSNEATK
ARSHLMESSNNFHPDLELVDLTPANLSELLSTDATVFKRIFLITQAAIKD
LESRISSMSTPPAALIVDVFSMDAFPVADRFGIKKYVFVTLNAWFLALTT
YVRTLDREIEGEYVDLPEPIAIPGCKPLRPEDVFDPMLSRSSDGYRPYLG
MSERLTKADGLLLNTWEALEPVSLKALRENEKLNQIMTPPLYPVGPVART
TVQEVVGNECLDWLSKQPTESVLYVALGSGGIISYKQMTELAWGLEMSRQ
RFIWVVRLPTMEKDGACRFFSDVNVKGPLEYLPEGFLDRNKELGMVLPNW
GPQDAILAHPSTGGFLSHCGWNSSLESIVNGVPVIAWPLYAEQKMNATLL
TEELGVAVRPEVLPTKAVVSRDEIEKMVRRVIESKEGKMKRNRARSVQSD
ALKAIEKGGSSYNTLIEVAKEFEKNHK
Ligand information
Ligand IDUDP
InChIInChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyXCCTYIAWTASOJW-XVFCMESISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
CACTVS 3.370O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
CACTVS 3.370O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
FormulaC9 H14 N2 O12 P2
NameURIDINE-5'-DIPHOSPHATE
ChEMBLCHEMBL130266
DrugBankDB03435
ZINCZINC000004490939
PDB chain6jtd Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6jtd Molecular and Structural Characterization of a Promiscuous C-Glycosyltransferase from Trollius chinensis.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		G23 I26 R253 G282 S283 W354 G355 Q357 H372 G374 N376 S377 E380 Y394
Binding residue
(residue number reindexed from 1)		G19 I22 R249 G278 S279 W350 G351 Q353 H368 G370 N372 S373 E376 Y390
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6jtd, PDBe:6jtd, PDBj:6jtd
PDBsum6jtd
PubMed31163097
UniProtA0A4Y5RXX8

[Back to BioLiP]