Structure of PDB 6jmt Chain A Binding Site BS01

Receptor Information
>6jmt Chain A (length=347) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTA
WPPTLLQMVETLYNNGANSIWEHSLLSIMSGRRKANPQDKVHPNKAEFIR
AKYQMLAFVHRLPCREDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQ
ANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYAR
QGGHHELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRADAALD
LSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLV
TVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6jmt GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
A266 K267 L273 L277 L281 S324 T326 R327 G330 L334 F337 E341 L345 D348
Binding residue
(residue number reindexed from 1)
A258 K259 L265 L269 L273 S313 T315 R316 G319 L323 F326 E330 L334 D337
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:6jmt, PDBe:6jmt, PDBj:6jmt
PDBsum6jmt
PubMed32780989
UniProtQ9JLQ2|GIT2_MOUSE ARF GTPase-activating protein GIT2 (Gene Name=Git2)

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