Structure of PDB 6jkv Chain A Binding Site BS01

Receptor Information
>6jkv Chain A (length=230) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSVSYYRSASYSHVGMVRKVNEDASLDAPEAGLWVVADGMGGHAAGDFVS
SLIVDTLRRIPAASSLPAYVGALRTGLAQVNERVRQEAGLRGVSVMGSTL
VLLAARGNQASCLWAGDSRLYRLRGGVLEAISRDHSYVQELLDNHHPRAN
VVTRAVGVHEQLELSEAALHVLPGDSFLLCSDGLNKTADDSELRDVLSHS
DPYAVVRSLVHLGLTRGAPDNITALVVRAF
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6jkv Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jkv Crystal structure of PppA from Pseudomonas aeruginosa, a key regulatory component of type VI secretion systems.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D41 G42
Binding residue
(residue number reindexed from 1)		D38 G39
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0050709 negative regulation of protein secretion

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6jkv, PDBe:6jkv, PDBj:6jkv
PDBsum6jkv
PubMed31208722
UniProtQ9I757

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