Structure of PDB 6ji2 Chain A Binding Site BS01

Receptor Information
>6ji2 Chain A (length=432) Species: 272557 (Aeropyrum pernix K1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESF
KFAWILDKMKEERERGITIDLTFMKFETKKYVFTIIDAPGHRDFVKNMIT
GASQADAAILVVSARKGEFEAGMSTEGQTREHLLLARTMGIEQIIVAVNK
MDAPDVNYDQKRYEFVVSVLKKFMKGLGYQVDKIPFIPVSAWKGDNLIER
SPNMPWYNGPTLVEALDQLQPPAKPVDKPLRIPVQNVYSIPGAGTVPVGR
VETGVLRVGDKVVFMPPGVVGEVRSIEMHYQQLQQAEPGDNIGFAVRGVS
KSDIKRGDVAGHLDKPPTVAEEFEARIFVIWHPSAITVGYTPVIHVHTAS
VSSRIIEIKAKLDPKTGQVVEQNPQFLKAGDAAIVRFKPVKPLVVEKFSE
IPQLGRFAMRDMNRTVGIGIVTDVKPAKVDIK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ji2 Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R140 G179 L180 F401 R409 I423
Binding residue
(residue number reindexed from 1)		R137 G176 L177 F398 R406 I420
Enzymatic activity
Catalytic site (original residue number in PDB) D16 K19 S20 T71 H94
Catalytic site (residue number reindexed from 1) D13 K16 S17 T68 H91
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ji2, PDBe:6ji2, PDBj:6ji2
PDBsum6ji2
PubMed31611569
UniProtQ9YAV0|EF1A_AERPE Elongation factor 1-alpha (Gene Name=tuf)

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