Structure of PDB 6jfu Chain A Binding Site BS01

Receptor Information

>6jfu Chain A (length=884) Species: 487 (Neisseria meningitidis)

NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGD
SLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSL
PNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNEGETADKELG
ALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRK
DLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLG
HCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLM
DEPYRKSKLTYAQARKLLGLEDTAFFKGLREASTLMEMKAYHAISRALEK
EGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALL
KHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKI
YLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKS
FKDRKEIEDTRYVNRFLCQFVADHIVFASNGQITNLLRGKVRAENDRHHA
LDAVVVACSTVAMQQKITRFVRYKTHFPQPWEFFAQEVMIRVFGKPDGKP
EFEEADTPEKLRTLLAEKLPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRS
AKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEA
YGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADN
GDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYT
FCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQF
RISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR

Ligand information

>6jfu Chain B (length=105)

ggucacucugcuauuuaacuuuacguuguagcucccuuucucgaaagaga
accguugcuacaauaaggccggugccgcaacgcucugccccuaggggcau
cguuu

........................<<<<<<<<..<..<<<<<....>>>>
>..>..>>>>>>>>..<<<....>>>..<<<<...<<<<<<..>>>>>>.
>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6jfu Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): S57 L58 A59 R62 R63 A65 R66 R69 R70 L71 R74 H77 R81 N108 P110 W111 H133 K136 H137 R138 G139 H191 I192 R193 N194 Q195 G197 R243 P244 A245 T259 K269 Q422 Y441 Y463 P466 R479 K511 R675 R746 R836 K837 M838 S839 G840 A841 H842 L846 R847 S848 R863 W865 V878 N879 R884 E885 K916 K917 Q920 L921 K923 A924 R926 N938 A942 T944 R953 A979 E980 C1073 R1074 P1080
• Binding residue (residue number reindexed from 1): S51 L52 A53 R56 R57 A59 R60 R63 R64 L65 R68 H71 R75 N102 P104 W105 H127 K130 H131 R132 G133 H185 I186 R187 N188 Q189 G191 R237 P238 A239 T253 K263 Q410 Y429 Y451 P454 R467 K499 R515 R572 R638 K639 M640 S641 G642 A643 H644 L648 R649 S650 R665 W667 V680 N681 R686 E687 K718 K719 Q722 L723 K725 A726 R728 N740 A744 T746 R755 A781 E782 C875 R876 P882

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Feb 17 07:48:20 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '6jfu', asym_id = 'A', bs = 'BS01', title = 'Structures of Neisseria meningitidis Cas9 Comple...ytically Poised and Anti-CRISPR-Inhibited States.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='6jfu', asym_id='A', bs='BS01', title='Structures of Neisseria meningitidis Cas9 Comple...ytically Poised and Anti-CRISPR-Inhibited States.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003676,0004519', uniprot = '', pdbid = '6jfu', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003676,0004519', uniprot='', pdbid='6jfu', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>