Structure of PDB 6jee Chain A Binding Site BS01

Receptor Information

>6jee Chain A (length=171) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHFF
RELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAIV
LEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTNI
QRLVGAGCGEYCFERLTLKHD

Ligand information

Ligand ID

InChI

InChI=1S/Cd/q+2

InChIKey

WLZRMCYVCSSEQC-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Cd++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Cd+2]

Formula

Name

CADMIUM ION

ChEMBL

DrugBank

ZINC

PDB chain

6jee Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6jee Coordination design of cadmium ions at the 4-fold axis channel of the apo-ferritin cage.
Resolution	1.3 Å
Binding residue (original residue number in PDB)	C161 C165
Binding residue (residue number reindexed from 1)	C158 C162
Annotation score	3

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005506	iron ion binding
GO:0008198	ferrous iron binding
GO:0008199	ferric iron binding
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005776	autophagosome
GO:0031410	cytoplasmic vesicle
GO:0044754	autolysosome
GO:0070288	ferritin complex

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Cellular Component

External links

PDB	RCSB:6jee, PDBe:6jee, PDBj:6jee
PDBsum	6jee
PubMed	30993287
UniProt	P02791\|FRIL_HORSE Ferritin light chain (Gene Name=FTL)

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