Structure of PDB 6j7s Chain A Binding Site BS01

Receptor Information
>6j7s Chain A (length=289) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYSSPPTNLRSLRDRLTQVAERQGVVFGRLQRHVAMIVVAQFAATLTDDT
GAPLLLVKGGSSLELRRGIPDSRTSKDFDTVARRDIELIHEQLADAGETG
WEGFTAIFTAPEEIDVPGMPVKPRRFTAKLSYRGRAFATVPIEVSSVEAG
NADQFDTLTSDALGLVGVPAAVAVPCMTIPWQIAQKLHAVTAVLEEPKVN
DRAHDLVDLQLLEGLLLDADLMPTRSACIAIFEARAQHPWPPRVATLPHW
PLIYAGALEGLDHLELARTVDAAAQAVQRFVARIDRATK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6j7s Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6j7s Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism.
Resolution2.102 Å
Binding residue
(original residue number in PDB)		G62 Q185
Binding residue
(residue number reindexed from 1)		G59 Q182
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6j7s, PDBe:6j7s, PDBj:6j7s
PDBsum6j7s
PubMed32382148
UniProtP96356

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