Structure of PDB 6j4v Chain A Binding Site BS01

Receptor Information
>6j4v Chain A (length=246) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQV
PNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKE
MTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGI
YCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKI
GLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j4v Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y123 K135 K157 C158 F191 H192 H193 R211 R212 Y239 H241
Binding residue
(residue number reindexed from 1)		Y75 K87 K109 C110 F143 H144 H145 R163 R164 Y191 H193
Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6j4v, PDBe:6j4v, PDBj:6j4v
PDBsum6j4v
PubMed31235911
UniProtQ86V25|VASH2_HUMAN Tubulinyl-Tyr carboxypeptidase 2 (Gene Name=VASH2)

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