Structure of PDB 6ijm Chain A Binding Site BS01

Receptor Information
>6ijm Chain A (length=337) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQR
SLVEVFKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPKRS
DSIGMSKRSYMEAVIQGLRSVSEVDIDFVTRKKIYVRLLLSIDRRETTES
AMETVKLALEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLH
CGEVPNPKEIQAMLDFKPHRIGHACFFKDEDWTKLKSFRIPVEICLTSNI
VTKSISSIDIHHFADLYNAKHPLILCTDDFGVFSTSLSNEYALAVRSLGL
SKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ijm Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ijm Alternative conformation induced by substrate binding for Arabidopsis thalianaN6-methyl-AMP deaminase.
Resolution2.016 Å
Binding residue
(original residue number in PDB)		H13 H15 H217 D295
Binding residue
(residue number reindexed from 1)		H14 H16 H200 D278
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
GO:0062154 N6-methyl-AMP deaminase activity
Biological Process
GO:0006401 RNA catabolic process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ijm, PDBe:6ijm, PDBj:6ijm
PDBsum6ijm
PubMed30721978
UniProtQ8LPL7|ADAL_ARATH N6-mAMP deaminase (Gene Name=MAPDA)

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