Structure of PDB 6i3p Chain A Binding Site BS01

Receptor Information
>6i3p Chain A (length=626) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIKEQRESLPVFQFRDQIIQAVKDNQILIVVGETGSGKTTQVTQYLAEAG
FTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFEDVTSPAT
KIKYMTDGMLQREILMDPDLKRYSVIMLDEAHERTIATDVLFALLKKTVK
RRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFPVEILYSREPEPDY
LEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKALGPSVPE
LIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETSITIDYIYYVVD
PGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLYTEA
AYQSEMLPTTIPDIQRQNLANTILLLKAMGINDLLRFDFMDPPPVNTMLT
ALEELYALGALDDEGLLTRLGRKMADFPMEPSLSKVLIASVDKGCSDEMV
TIVSMLNLQQIFYRPKDKQQQADQKKAKFHDPTGDHLTLLNVYNAWKNSG
YSNAWCFENYIQARAMRRARDVRQQIVKIMERHRHPIISCGRDTDKIRQA
LCAGFFRNTARKDYKTLTEGTPVYLHPSSALFGKQAEWVLYHELVLTTKE
YMHFTTAIEPKWLVEAAPTFFKLAPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i3p Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R612 R639 T654 G656 M657 R660 G774 Q775 S806 T831 N832 S837 K853 L866 N919 P976 Q1007 R1012 Q1073 H1128 P1129 F1134 V1147 T1149 K1151 Y1153 H1155
Binding residue
(residue number reindexed from 1)		R64 R91 T106 G108 M109 R112 G226 Q227 S258 T283 N284 S289 K305 L318 N371 P428 Q459 R464 Q525 H576 P577 F582 V595 T597 K599 Y601 H603
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6i3p, PDBe:6i3p, PDBj:6i3p
PDBsum6i3p
PubMed30828714
UniProtG0S700

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