Structure of PDB 6i28 Chain A Binding Site BS01

Receptor Information
>6i28 Chain A (length=161) Species: 654905 (Cydia pomonella granulosis virus (isolate Mexican)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYDATRINQDLFVGGFYGDVIAMRHFVRQNNVGCVVSLIDSDVAPIKRAL
YLPDGDHLHVHCEDDAKCGALADNLEMLFNYLWLKIHNEHKTVLIHCHAG
VSRSATLAIYYIMRTNQIDYEQAFQYVYGKRAVHPSEHFVELLKGKCVYS
YVDNKLVVRVE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6i28 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6i28 Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		H98 A99 R103
Binding residue
(residue number reindexed from 1)		H98 A99 R103
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0008330 protein tyrosine/threonine phosphatase activity
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0033550 MAP kinase tyrosine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0043409 negative regulation of MAPK cascade

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Molecular Function
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Biological Process
External links
PDB RCSB:6i28, PDBe:6i28, PDBj:6i28
PDBsum6i28
PubMed30950823
UniProtQ91EV7

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