Structure of PDB 6i0v Chain A Binding Site BS01

Receptor Information

>6i0v Chain A (length=346) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VKARQHITVRLPKKARAMIVGITNVFKDKYPIADKLKVIPEYDVIEQDLC
KLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEHRASN
ATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNS
MGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITLMVIY
FLQLQALLPPIAMLQIEQAVLVGPWVVNFAQKSFSELGLQQLKATVPVIK
GFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVSDNP
ECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLE

Ligand information

>6i0v Chain B (length=5) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acagu

.....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6i0v Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Resolution	1.851 Å
Binding residue (original residue number in PDB)	F265 D280 I323 A326 R327 V328 D343 N347 G350 N353 Y390 Q507 K526
Binding residue (residue number reindexed from 1)	F67 D82 I125 A128 R129 V130 D145 N149 G152 N155 Y192 Q305 K324

Enzymatic activity

Enzyme Commision number

2.7.7.52: RNA uridylyltransferase.

External links

PDB	RCSB:6i0v, PDBe:6i0v, PDBj:6i0v
PDBsum	6i0v
PubMed	30462292
UniProt	Q9VI58\|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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