Structure of PDB 6i0t Chain A Binding Site BS01

Receptor Information
>6i0t Chain A (length=348) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIEQDL
CKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEHRAS
NATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLN
SMGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITLMVI
YFLQLQALLPPIAMLQIEDQAVLVGPWVVNFAQKSFSELGLQQLKATVPV
IKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVSD
NPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i0t Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
F265 R327 V328 G350 N353 Y390
Binding residue
(residue number reindexed from 1)
F68 R130 V131 G153 N156 Y193
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
External links
PDB RCSB:6i0t, PDBe:6i0t, PDBj:6i0t
PDBsum6i0t
PubMed30462292
UniProtQ9VI58|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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