Structure of PDB 6hsn Chain A Binding Site BS01

Receptor Information
>6hsn Chain A (length=411) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPF
PASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
CGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGE
CVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLL
PGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVI
ITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVR
KIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLD
PRPEYHRCILTWHHQEPLPWAQSTLMSMRSANGLLMLPPKTEQYVELHKG
EVVDVMVIGRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hsn Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		M326 D327 F330 R653 Y673 M711 P713 V727 D729
Binding residue
(residue number reindexed from 1)		M8 D9 F12 R335 Y355 M386 P388 V402 D404
Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:6hsn, PDBe:6hsn, PDBj:6hsn
PDBsum6hsn
PubMed30704910
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

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