Structure of PDB 6hpd Chain A Binding Site BS01

Receptor Information
>6hpd Chain A (length=955) Species: 1347342 (Formosa agariphila KMM 3901) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVITSSERTTYNFNVDWKFIKSNPKQAQDINYNDATWETISCPHTFNDVD
TFDDLSHGHHDGEDNQWRGTVWYRKHFKLPKDDKGKKVFIEFESVRQIAD
VYINGVHLGQNQTGFIPFGFDLTPHLKFGEENIIAVKVNNDRGDHFRENF
PLVWNHEHWHPTHGGIYRNVFLHTMDPLHITLPLYDNLETVGTYVYAENI
SEKSADITVETEIQNEHAENKNITLVTQIVDNDGAVVAHSNKNVAIPSGQ
KMKVTTVTNIQNPQLWYTRYPYMYKVVSAIKESNKVIDTYESPLGIRNFD
FNKDSGFWINGEQIKLHGWGQKPTNAWAGLGAALPDWLRDFTFKLMDEAG
GNFIRWGHCAASPAEVDMGDKYGFVTLMPGVSGESEDEGETWDIRYKAFK
DLIVYYRNHPSIFIWEGGNWAESEAHYKEILEAIKTFDPKGKRLMGNRRA
DVKNDSEGYVSIEIGTEGWEREYPDLPIIESEYNREEAPRRIWDKNSPDD
NFYNHPNISKNTYKLSSEEFAVRQADHWWNKMGKKAYHSGGANWIFSDGP
HGGRCPTEVTRASGEVDAVRLPKEAFYALKAMWRPEPQVHIVGHWNYEVG
TKKTMYVMSNCASVKLYVNDKLVGTNSNPENGYVFKFDNVAWESGKIKAE
GFIDDALKTTQTKETTGEPAALKLTSITGPEGWLADGSDVALIDVEVVDA
QGRRCPLAKGRVDFTISGPAIWRGGYNSGKPNSTNNLFLDIEAGINRVAV
RSVLESGTVTIMAKKPGFKDVSVTLKSLPIDFNNGLTTTLPQVYTNVLTK
EPLPEHIPEMPESELFRKFSYTGDGKAMLRTNMHWGKKAYTDLEYNYTVL
PRYLNESEYVRTPNSDNRYWARDQLQFIAGKKMHIYVLHDDTVPRPEFLL
RDYEDTGDNVNVVGASMSVFHRVAEEGESIIMAGNSDGDAPENCRMYTVM
VKEFK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6hpd Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6hpd A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan.
Resolution2.43 Å
Binding residue
(original residue number in PDB)		N570 W571 I572 S590 E592
Binding residue
(residue number reindexed from 1)		N543 W544 I545 S563 E565
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.31: beta-glucuronidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566 beta-glucuronidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0042597 periplasmic space

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hpd, PDBe:6hpd, PDBj:6hpd
PDBsum6hpd
PubMed31285597
UniProtT2KN75|PLH17_FORAG Beta-glucuronidase (Gene Name=BN863_22060)

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