Structure of PDB 6hm5 Chain A Binding Site BS01
Receptor Information
>6hm5 Chain A (length=251) Species:
9031
(Gallus gallus) [
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FLVKFVKSSGSSEYFLKALESIEHLQILEEEAALNIKENDKSLYICDPFT
GVVFNHLKKLGCRIVGPQVVLYCMQSQRCVPRAEYPVYNMTMADVTISCT
TLDKDVREEVHKYVQMMGGRVYRDLNMSVTHLIAGEVGSKKYLVAASLKK
PVLLPSWVKTLWDKSQQRMMRYTDVNMEDYACPVFLGCTICVTGLSSSDR
KEVQRLTAEHGGQYSGMNECTHLIVQVHCVPVQWFSDSIEKGFCQDETMY
K
Ligand information
>6hm5 Chain B (length=8) Species:
9606
(Homo sapiens) [
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SPVLAEDS
Receptor-Ligand Complex Structure
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PDB
6hm5
BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands.
Resolution
2.33004 Å
Binding residue
(original residue number in PDB)
T114 T115 K118 R121 R137 D138 L139 N140 M141 K155
Binding residue
(residue number reindexed from 1)
T100 T101 K104 R107 R123 D124 L125 N126 M127 K141
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6hm5
,
PDBe:6hm5
,
PDBj:6hm5
PDBsum
6hm5
PubMed
30295604
UniProt
A0A1D5P3M9
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