Structure of PDB 6hc7 Chain A Binding Site BS01

Receptor Information

>6hc7 Chain A (length=406) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RELPFKAKHAYSTISQLSEAIGPRIAGTAAEKKSALLIASSMRKLKLDVK
VQRFNIPDRLEGTLSSAGRDILLQAASGSAPTEEQGLTAPLYNAGLGYQK
DFTADAKGKIALISRGDLTYYEKAKNAEAAGAKAVIIYNNKESLVPMTPN
LSGNKVGIPVVGIKKEDGEALTQQKEATLKLKAFTNQTSQNIIGIKKPKN
IKHPDIVYVTAHYDSVPFSPGANDNGSGTSVMLEMARVLKSVPSDKEIRF
IAFGAEELGLLGSSHYVDHLSEKELKRSEVNFNLDMVGTSWEKASELYVN
TLDGQSNYVWESSRTAAEKIGFDSLSLTQGGSSDHVPFHEAGIDSANFIW
GDPETEEVEPWYHTPEDSIEHISKERLQQAGDLVTAAVYEAVKKKAKASD
IFEDIK

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6hc7 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6hc7 The crystal structure of BSAP, a zinc aminopeptidase from Bacillus subtilis (medium resolution)
Resolution	2.5 Å
Binding residue (original residue number in PDB)	H250 D262 D323
Binding residue (residue number reindexed from 1)	H212 D224 D285
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.4.11.10: bacterial leucyl aminopeptidase.
3.4.11.6: aminopeptidase B.

Gene Ontology

	Molecular Function
GO:0008235	metalloexopeptidase activity

	Biological Process
GO:0006508	proteolysis

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6hc7, PDBe:6hc7, PDBj:6hc7
PDBsum	6hc7
PubMed
UniProt	P25152\|BSAP_BACSU Aminopeptidase YwaD (Gene Name=ywaD)

[Back to BioLiP]