Structure of PDB 6h3a Chain A Binding Site BS01

Receptor Information
>6h3a Chain A (length=266) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPTVVDCPVCKQQCFS
KDIVENYFMRDERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQY
QFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQ
VDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQ
EHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQ
WDLNAWTKSAEAFGKI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6h3a Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6h3a A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Resolution5.505 Å
Binding residue
(original residue number in PDB)		C83 H85 C117 C120
Binding residue
(residue number reindexed from 1)		C25 H27 C41 C44
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6h3a, PDBe:6h3a, PDBj:6h3a
PDBsum6h3a
PubMed31204252
UniProtQ13263|TIF1B_HUMAN Transcription intermediary factor 1-beta (Gene Name=TRIM28)

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