Structure of PDB 6gtg Chain A Binding Site BS01 |
| >6gtg Chain A (length=1298) Species: 401614 (Francisella tularensis subsp. novicida U112)
[Search protein sequence]
[Download receptor structure]
[Download structure with residue number starting from 1]
[View receptor structure]
|
IYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQ
IIDKYHQFFIEEILSSVCISEDLLQNYSDVYFKLKKSDDDNLQKDFKSAK
DTIKKQISEYIKDSEKFKNLFNQNLIDAKKGQESDLILWLKQSKDNGIEL
FKANSDITDIDEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYR
IVDDNLPKFLENKAKYESLKDKAPEAINYEQIKKDLAEELTFDIDYKTSE
VNQRVFSLDEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINE
YINLYSQQINDKTLKKYKMSVLFKQILSDTESKSFVIDKLEDDSDVVTTM
QSFYEQIAAFKTVEEKSIKETLSLLFDDLKAQKLDLSKIYFKNDKSLTDL
SQQVFDDYSVIGTAVLEYITQQIAPKNLDNPSKKEQELIAKKTEKAKYLS
LETIKLALEEFNKHRDIDKQCRFEEILANFAAIPMIFDEIAQNKDNLAQI
SIKYQNQGKKDLLQASAEDDVKAIKDLLDQTNNLLHKLKIFHISQSEDKA
NILDKDEHFYLVFEECYFELANIVPLYNKIRNYITQKPYSDEKFKLNFEN
STLANGWDKNKEPDNTAILFIKDDKYYLGVMNKKNNKIFDDKAIKENKGE
GYKKIVYKLLPGANKMLPKVFFSAKSIKFYNPSEDILRIRNHSTHTKNGS
PQKGYEKFEFNIEDCRKFIDFYKQSISKHPEWKDFGFRFSDTQRYNSIDE
FYREVENQGYKLTFENISESYIDSVVNQGKLYLFQIYNKDFSAYSKGRPN
LHTLYWKALFDERNLQDVVYKLNGEAELFYRKQSIPKKITHPAKEAIANK
NKDNPKKESVFEYDLIKDKRFTEDKFFFHCPITINFKSSGANKFNDEINL
LLKEKANDVHILSIDRGERHLAYYTLVDGKGNIIKQDTFNIIGNDRMKTN
YHDKLAAIEKDRDSARKDWKKINNIKEMKEGYLSQVVHEIAKLVIEYNAI
VVFQDLNFGFKRGRFKVEKQVYQKLEKMLIEKLNYLVFKDNEFDKTGGVL
RAYQLTAPFETFKKMGKQTGIIYYVPAGFTSKICPVTGFVNQLYPKYESV
SKSQEFFSKFDKICYNLDKGYFEFSFDYKNFGDKAAKGKWTIASFGSRLI
NFRNSDKNHNWDTREVYPTKELEKLLKDYSIEYGHGECIKAAICGESDKK
FFAKLTSVLNTILQMRNSKTGTELDYLISPVADVNGNFFDSRQAPKNMPQ
DADANGAYHIGLKGLMLLGRIKNNQEGKKLNLVIKNEEYFEFVQNRNN |
|
|
|
| Global view | Local view | Structure summary |
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
| PDB | 6gtg Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. |
| Resolution | 3.27 Å |
Binding residue
(original residue number in PDB) | S14 K15 T16 R18 K51 N185 R186 R202 F289 T295 K296 L306 Q309 F325 K326 I328 L329 K447 A448 H538 Y579 N580 R583 N790 K791 Y796 S797 K798 R800 L803 H804 R833 H843 I849 A850 N851 K852 N856 K858 S861 F863 Y865 L867 K869 K871 R872 F873 F879 H881 R948 M949 Y953 K956 R968 K969 E979 M980 G983 S986 H990 R1014 F1017 K1018 K1034 K1041 N1160 |
Binding residue
(residue number reindexed from 1) | S12 K13 T14 R16 K49 N183 R184 R200 F287 T293 K294 L304 Q307 F323 K324 I326 L327 K445 A446 H536 Y577 N578 R581 N788 K789 Y794 S795 K796 R798 L801 H802 R831 H841 I847 A848 N849 K850 N854 K856 S859 F861 Y863 L865 K867 K869 R870 F871 F877 H879 R946 M947 Y951 K954 R966 K967 E977 M978 G981 S984 H988 R1012 F1015 K1016 K1032 K1039 N1158 |
|
|
| Enzyme Commision number |
3.1.21.1: deoxyribonuclease I.
4.6.1.22: Bacillus subtilis ribonuclease. |
|
|
|
|
|
