Structure of PDB 6gte Chain A Binding Site BS01 |
| >6gte Chain A (length=1274) Species: 401614 (Francisella tularensis subsp. novicida U112)
[Search protein sequence]
[Download receptor structure]
[Download structure with residue number starting from 1]
[View receptor structure]
|
IYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQ
IIDKYHQFFIEEILSSVCISEDLLQNYSDVYFKLKKSDDDNLQKDFKSAK
DTIKKQISEYIKDSEKFKNLFNQNLIDAKKGQESDLILWLKQSKDNGIEL
FKANSDITDIDEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYR
IVDDNLPKFLENKAKYESLKDKAPEAINYEQIKKDLAEELTFDIDYKTSE
VNQRVFSLDEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINE
YINLYSQQINDKTLKKYKMSVLFKQILSDTEKLEDDSDVVTTMQSFYEQI
AAFKTVEEKSIKETLSLLFDDLKAQKLDLSKIYFKNDKSLTDLSQQVFDD
YSVIGTAVLEYITQQIAPKNLDNPSKKEQELIAKKTEKAKYLSLETIKLA
LEEFNKHRDIDKQCRFEEILANFAAIPMIFDEIAQNKDNLAQISIKYQNQ
GKKDLLQASAEDDVKAIKDLLDQTNNLLHKLKIFHISQSEDKANILDKDE
HFYLVFEECYFELANIVPLYNKIRNYITQKPYSDEKFKLNFENSTLANGW
DKNKEPDNTAILFIKDDKYYLGVMNKKNNKIFDDKAIKENKGEGYKKIVY
KLLPGANKMLPKVFFSAKSIKFYNPSEDILRIRNHSTHTKNGSPQKGYEK
FEFNIEDCRKFIDFYKQSISKHPEWKDFGFRFSDTQRYNSIDEFYREVEN
QGYKLTFENISESYIDSVVNQGKLYLFQIYNKDFSAYSKGRPNLHTLYWK
ALFDERNLQDVVYKLNGEAELFYRKQSIPKKITHPAKEAIANKNKDNPKK
ESVFEYDLIKDKRFTEDKFFFHCPITINFKSSGANKFNDEINLLLKEKAN
DVHILSIDRGERHLAYYTLVDGKGNIIKQDTFNIIGNDRMKTNYHDKLAA
IEKDRDSARKDWKKINNIKEMKEGYLSQVVHEIAKLVIEYNAIVVFQDLN
QVYQKLEKMLIEKLNYLVFKDNEFDKTGGVLRAYQLTAPFETFKKMGKQT
GIIYYVPAGFTSKICPVTGFVNQLYPKYESVSKSQEFFSKFDKICYNLDK
GYFEFSFDYKNFGDKAAKGKWTIASFGSRLINFRNSNWDTREVYPTKELE
KLLKDYSIEYGHGECIKAAICGESDKKFFAKLTSVLNTILQMRNSKTGTE
LDYLISPVADVNGNFFDSRQAPKNMPQDADANGAYHIGLKGLMLLGRIKN
NQEGKKLNLVIKNEEYFEFVQNRN |
|
|
|
| Global view | Local view | Structure summary |
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
| PDB | 6gte Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. |
| Resolution | 4.07 Å |
Binding residue
(original residue number in PDB) | S14 T16 R18 K51 N185 R186 R202 K326 I328 L329 N790 K791 Y796 S797 K798 R800 N802 L803 H804 R833 I849 A850 N851 N853 K858 F863 Y865 L867 K869 D870 K871 R872 F873 F879 D947 M949 K956 N976 M980 H990 K1034 K1041 |
Binding residue
(residue number reindexed from 1) | S12 T14 R16 K49 N183 R184 R200 K324 I326 L327 N781 K782 Y787 S788 K789 R791 N793 L794 H795 R824 I840 A841 N842 N844 K849 F854 Y856 L858 K860 D861 K862 R863 F864 F870 D938 M940 K947 N967 M971 H981 K1013 K1020 |
|
|
| Enzyme Commision number |
3.1.21.1: deoxyribonuclease I.
4.6.1.22: Bacillus subtilis ribonuclease. |
|
|
|
|
|
