Structure of PDB 6grd Chain A Binding Site BS01

Receptor Information
>6grd Chain A (length=407) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNGVSTAMAKRLIRLFGFTAH
DAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGSKGGP
PTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGDYLPDGIPGCGIKVACQ
AAKAGFGKELCRIKRADKEAITEWKQRLLHELRTNESGFFRTKHKALEIP
ENFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFD
WTFRPGAIKLIKVLAPGLLVQRCLDRKKEESTLVKGISMRREHFSTDATP
ELRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVED
WEEGQRS
Ligand information
Receptor-Ligand Complex Structure
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PDB6grd A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.
Resolution2.66 Å
Binding residue
(original residue number in PDB)
Y7 D141 T257 K258 H259
Binding residue
(residue number reindexed from 1)
Y6 D126 T242 K243 H244
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:6grd, PDBe:6grd, PDBj:6grd
PDBsum6grd
PubMed30247722
UniProtG0RYN2

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