Structure of PDB 6grc Chain A Binding Site BS01

Receptor Information
>6grc Chain A (length=406) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNGVSTAMAKRLIRLFGFTAH
DAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGSKGGP
PTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGDYLPDGIPGCGIKVACQ
AAKAGFGKELCRIKRDKEAITEWKQRLLHELRTNESGFFRTKHKALEIPE
NFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDW
TFRPGAIKLIKVLAPGLLVQRCLDRKKEESTLVKGISMRREHFSTDATPE
LRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDW
EEGQRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6grc A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.
Resolution2.452 Å
Binding residue
(original residue number in PDB)
Y7 D141 K258 H259 A261
Binding residue
(residue number reindexed from 1)
Y6 D126 K242 H243 A245
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:6grc, PDBe:6grc, PDBj:6grc
PDBsum6grc
PubMed30247722
UniProtG0RYN2

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