Structure of PDB 6grb Chain A Binding Site BS01

Receptor Information
>6grb Chain A (length=398) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKSTAMAKRLIRLFGFTAHD
APGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHV
TLHDAKKIAEGPSGLDREGMVLVALMSGGDYLPDGIPGCGIKVACQAAKA
GFGKELCRIKRAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEV
LRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAI
KLIKVLAPGLLVQRCLDRKEESTLVKGISMRREHFSTDATPELRVSFIPA
ELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS
Ligand information
Receptor-Ligand Complex Structure
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PDB6grb A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y7 E140 D141 T257 K258 H259
Binding residue
(residue number reindexed from 1)		Y6 E124 D125 T234 K235 H236
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:6grb, PDBe:6grb, PDBj:6grb
PDBsum6grb
PubMed30247722
UniProtG0RYN2

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