Structure of PDB 6ghs Chain A Binding Site BS01

Receptor Information
>6ghs Chain A (length=285) Species: 37925 (Thermocrispum agreste) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYKRTFGHIPGHPEGSTYSNRRQVQKAGLHAHLQAGISGTAKQGADAIVL
NGGYPDDRDYGDEIIYTGHGGQDPVTKKQIRDQDLDDPGNAGLVRSQLEG
LPVRVIRGAGGEKPYSPSSGYRYDGLYKVVAHWFANHEDAPQFRVCQFQL
VKIYDQVAAGVVVDNPVRSAQVVKNVKGWHKHRCQVCGIVIEVDVGPYSQ
GAHIRPLGRKHGGPDVESNMLCLCPNDHVRFDNGALYITDDLKVVNALNG
EVIGPLRVHPRHVIDLDHIRYHRSQLPNIPLEGSS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ghs Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ghs Crystal structure of the modification-dependent SRA-HNH endonuclease TagI.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		C210 C213 C250 D253
Binding residue
(residue number reindexed from 1)		C184 C187 C224 D227
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:6ghs, PDBe:6ghs, PDBj:6ghs
PDBsum6ghs
PubMed30202937
UniProtA0A3F2YM30

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