Structure of PDB 6ghn Chain A Binding Site BS01
Receptor Information
>6ghn Chain A (length=269) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDQDTELVETRPAGDGTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPEPVTLRW
Ligand information
>6ghn Chain P (length=9) Species:
1762
(Mycobacteriaceae) [
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RLPAKAPLF
Receptor-Ligand Complex Structure
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PDB
6ghn
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution
2.542 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 S66 I73 N77 L81 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E63 S66 I73 N77 L81 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ghn
,
PDBe:6ghn
,
PDBj:6ghn
PDBsum
6ghn
PubMed
30087334
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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