Structure of PDB 6gh1 Chain A Binding Site BS01
Receptor Information
>6gh1 Chain A (length=274) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>6gh1 Chain P (length=9) Species:
83332
(Mycobacterium tuberculosis H37Rv) [
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RLPAKAPLL
Receptor-Ligand Complex Structure
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PDB
6gh1
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y7 H9 R62 E63 N77 Y84 W97 H99 S143 K146 E152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 R62 E63 N77 Y84 W97 H99 S143 K146 E152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6gh1
,
PDBe:6gh1
,
PDBj:6gh1
PDBsum
6gh1
PubMed
30087334
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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