Structure of PDB 6gg8 Chain A Binding Site BS01
Receptor Information
>6gg8 Chain A (length=242) Species:
9606
(Homo sapiens) [
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SPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKV
LPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFN
EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL
KSQAAFEEMRTNYIKELRKMVTKSSWQRFYQLTKLLDSMHDLVSDLLEFC
FYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
Ligand information
>6gg8 Chain B (length=10) Species:
9606
(Homo sapiens) [
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KSLLQQLLTE
Receptor-Ligand Complex Structure
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PDB
6gg8
Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
V781 K785 L795 I799 A958 E962
Binding residue
(residue number reindexed from 1)
V45 K49 L59 I63 A216 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6gg8
,
PDBe:6gg8
,
PDBj:6gg8
PDBsum
6gg8
PubMed
30596500
UniProt
P08235
|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)
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