Structure of PDB 6gev Chain A Binding Site BS01
Receptor Information
>6gev Chain A (length=247) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
YFSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWA
KVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHTNSQFLYFAPDLV
FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKD
GLKSQAAFEEMRTNYIKELRKMVTKSPNNSGQSWQRFYQLTKLLDSMHDL
VSDLLEFCFYTFRESKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
Ligand information
>6gev Chain B (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KSLLQQLLTE
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6gev
Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
Resolution
1.54 Å
Binding residue
(original residue number in PDB)
V781 K785 L795 I799 A958 M959 E962
Binding residue
(residue number reindexed from 1)
V47 K51 L61 I65 A221 M222 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6gev
,
PDBe:6gev
,
PDBj:6gev
PDBsum
6gev
PubMed
30596500
UniProt
P08235
|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)
[
Back to BioLiP
]
