Structure of PDB 6gen Chain A Binding Site BS01

Receptor Information
>6gen Chain A (length=97) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKEIKLARRLRGE
Ligand information
>6gen Chain I (length=173) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcattaatgcatccgcggccgccctggagaatcccggtgccgaggccgct
caattggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgt
cccccgcgttttaaccgccaaggggattactccctagtctccaggcacgt
gtcagatatatacatcctgtgca
Receptor-Ligand Complex Structure
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PDB6gen Structure and dynamics of the yeast SWR1-nucleosome complex.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R83 F84 Q85 S86 R116 T118
Binding residue
(residue number reindexed from 1)		R47 F48 Q49 S50 R80 T82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008823 cupric reductase (NADH) activity
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of DNA-templated transcription
GO:0006878 intracellular copper ion homeostasis
GO:0009060 aerobic respiration
GO:0009303 rRNA transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0043935 sexual sporulation resulting in formation of a cellular spore
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gen, PDBe:6gen, PDBj:6gen
PDBsum6gen
PubMed30309918
UniProtP61830|H3_YEAST Histone H3 (Gene Name=HHT1)

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