Structure of PDB 6gb6 Chain A Binding Site BS01

Receptor Information
>6gb6 Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPHSLRYFVTAVSRPGLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRAR
WMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISG
CEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQA
GEAERLRAYLEGTCVEWLRRYLKATLLRTDSPKAHVTHHSRPEDKVTLRC
WALGFYPADITLTWQLNGEELIQDMELVETRPAGDGTFQKWASVVVPLGK
EQYYTCHVYHQGLPEPLTLRWEP
Ligand information
Ligand IDLEU
InChIInChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChIKeyROHFNLRQFUQHCH-YFKPBYRVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CC(C)C[C@@H](C(=O)O)N
CACTVS 3.341CC(C)C[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CC(C)CC(C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CC(C)C
CACTVS 3.341CC(C)C[CH](N)C(O)=O
FormulaC6 H13 N O2
NameLEUCINE
ChEMBLCHEMBL291962
DrugBankDB00149
ZINCZINC000003645145
PDB chain6gb6 Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gb6 Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		D77 Y84 Y116 T143 K146 W147
Binding residue
(residue number reindexed from 1)		D77 Y84 Y116 T143 K146 W147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6gb6, PDBe:6gb6, PDBj:6gb6
PDBsum6gb6
PubMed30808808
UniProtP01901|HA1B_MOUSE H-2 class I histocompatibility antigen, K-B alpha chain (Gene Name=H2-K1)

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