Structure of PDB 6g84 Chain A Binding Site BS01

Receptor Information
>6g84 Chain A (length=356) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VYLDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFYNSFHLDFGPM
NIGHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANAACMLCCYMIL
VQAWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDVVYGVWRAKEK
GLIDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQEDHLNQPFKSVL
NFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNF
VGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRF
IRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGLYPLISLEEY
RLQKKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6g84 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		L14 H67 L70 Q106 W108 Q112
Binding residue
(residue number reindexed from 1)		L10 H63 L66 Q102 W104 Q108
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:6g84, PDBe:6g84, PDBj:6g84
PDBsum6g84
PubMed30455435
UniProtQ00684|CDC14_YEAST Tyrosine-protein phosphatase CDC14 (Gene Name=CDC14)

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