Structure of PDB 6g0s Chain A Binding Site BS01

Receptor Information
>6g0s Chain A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6g0s Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution1.48 Å
Binding residue
(original residue number in PDB)
W81 K91 L92 D145 I146
Binding residue
(residue number reindexed from 1)
W40 K50 L51 D104 I105
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6g0s, PDBe:6g0s, PDBj:6g0s
PDBsum6g0s
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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