Structure of PDB 6g0q Chain A Binding Site BS01
Receptor Information
>6g0q Chain A (length=125) Species:
9606
(Homo sapiens) [
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MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTE
Ligand information
>6g0q Chain B (length=10) Species:
9606
(Homo sapiens) [
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SGKGKKKRGY
Receptor-Ligand Complex Structure
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PDB
6g0q
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
1.4 Å
Binding residue
(original residue number in PDB)
Q78 W81 V87 L92 D145 I146 M149
Binding residue
(residue number reindexed from 1)
Q36 W39 V45 L50 D103 I104 M107
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6g0q
,
PDBe:6g0q
,
PDBj:6g0q
PDBsum
6g0q
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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