Structure of PDB 6g0o Chain A Binding Site BS01
Receptor Information
>6g0o Chain A (length=125) Species:
9606
(Homo sapiens) [
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SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
>6g0o Chain B (length=11) Species:
9606
(Homo sapiens) [
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HFPKGIKQIKY
Receptor-Ligand Complex Structure
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PDB
6g0o
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
1.4 Å
Binding residue
(original residue number in PDB)
W81 P82 V87 L94 P95 D96 Y139 K141 D145 I146 M149
Binding residue
(residue number reindexed from 1)
W40 P41 V46 L53 P54 D55 Y98 K100 D104 I105 M108
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6g0o
,
PDBe:6g0o
,
PDBj:6g0o
PDBsum
6g0o
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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