Structure of PDB 6fok Chain A Binding Site BS01

Receptor Information
>6fok Chain A (length=651) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAPSVVTGVAQSSPLTIVTNPKEPRQPVPASDGADYLKTIPGFAVIRNGG
SNGDPVLRGMFGSRLNILTNGGMMLGACPNRMDAPTSYISPETYDKLTVI
KGPQTVLWGPGASAGTILFEREPERFGELGSRVNASLLAGSNGRFDKVLD
AAAGNRLGYLRFTGNHAQSDDYEDGAGNTVPSRWKKWNGDVAVGWTPDED
TLIELTAGKGDGEARYAGRGMDGSQFKRESLGLRFVKSNVSDVLEKVEAQ
VYYNYADHIMDNFRLRTPDPSSMMPMPMASQVDRRTLGGRLAATWRWDDF
KLVTGVDAMRNEHRARGSKYDMMTDYYTDADQFPWSKDAVFHNYGAFGEL
TWFAAERDRLIGGLRLDRASVKDYRQTLKHAMANPTANDTRADTLPSGFV
RYEHDLADSPTTLYAGLGHAERFPDYWELFSPKRGPNGSVNAFDKIKPEK
TTQLDFGLQYNGDKLQAWASGYVGVVQDFILFSYREMGSSTQATNVDARI
MGGELGASYQLTGNWKTDASLAYAWGKNSSDDRALPQIPPLEARFGLTYE
EGDWSAGSLWRVVAPQNRIARDQGNVVGKDFDKSAGFGVFSLNGAYRVTR
NVKLSAGVDNLFDKDYTEHLNKAGDAGFGFSANETVPEPGRTFWTKVDFS
F
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain6fok Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6fok Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site.
Resolution1.97 Å
Binding residue
(original residue number in PDB)		C89 M93 H269 M271
Binding residue
(residue number reindexed from 1)		C78 M82 H258 M260
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015344 siderophore uptake transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0033214 siderophore-dependent iron import into cell
GO:0044718 siderophore transmembrane transport
Cellular Component
GO:0009279 cell outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fok, PDBe:6fok, PDBj:6fok
PDBsum6fok
PubMed34762655
UniProtG3XD89

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