Structure of PDB 6fmx Chain A Binding Site BS01

Receptor Information

>6fmx Chain A (length=201) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168)

MYKPVSLFLFFLILAAAIHTNAVQSADEAISKAAVLIRQPWLNEVMTGIT
HLGASSFLLPLIVIIGAGMFFYRKTWDGLLMLLVFGTDRLLNKVLKEWIE
RVRPDFAPLVHESSFSFPSGHSMNAACVYPVIAYFLVKHLPFLSKHKKMV
YIIAGVIAVLVGISRVYLGVHFVTDVLGGFSLGLLLFFLVKGFDEKIKRF
R

Ligand information

• Ligand ID: WO4
• InChI: InChI=1S/4O.W/q;;2*-1;
• InChIKey: PBYZMCDFOULPGH-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-][W](=O)(=O)[O-]
  ACDLabs 10.04
  CACTVS 3.341: [O-][W]([O-])(=O)=O
• Formula: O4 W
• Name: TUNGSTATE(VI)ION
• PDB chain: 6fmx Chain A Residue 306

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6fmx In situ serial crystallography for rapid de novo membrane protein structure determination.
• Resolution: 1.79 Å
• Binding residue (original residue number in PDB): K96 R103 G120 H121 R165 H171
• Binding residue (residue number reindexed from 1): K96 R103 G120 H121 R165 H171
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.1.3.27: phosphatidylglycerophosphatase.

Gene Ontology

Molecular Function

• GO:0008962 phosphatidylglycerophosphatase activity
• GO:0016787 hydrolase activity

Biological Process

• GO:0008610 lipid biosynthetic process
• GO:1901137 carbohydrate derivative biosynthetic process

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:6fmx, PDBe:6fmx, PDBj:6fmx
• PDBsum: 6fmx
• PubMed: 30272004
• UniProt: O34349|PGPB_BACSU Phosphatidylglycerophosphatase B (Gene Name=pgpB)