Structure of PDB 6fbr Chain A Binding Site BS01

Receptor Information
>6fbr Chain A (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEE
Ligand information
Receptor-Ligand Complex Structure
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PDB6fbr Modulation of RXR-DNA complex assembly by DNA context.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
G144 K145 H146 Y147 K156 K160 R164 Q206 E208
Binding residue
(residue number reindexed from 1)
G14 K15 H16 Y17 K26 K30 R34 Q76 E78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:6fbr, PDBe:6fbr, PDBj:6fbr
PDBsum6fbr
PubMed30476562
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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