Structure of PDB 6f65 Chain A Binding Site BS01

Receptor Information

>6f65 Chain A (length=285) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLT
SEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHD
EAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDS
PEAVIRAATVYNMIVEGTLFESGYYTFRQIYKKAGLFPGLLQGIDYLNMD
EGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKR
QQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRT

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

6f65 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6f65 Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase.
Resolution	1.948 Å
Binding residue (original residue number in PDB)	E102 E167 E202 H205
Binding residue (residue number reindexed from 1)	E101 E166 E201 H204
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.17.4.1: ribonucleoside-diphosphate reductase.

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009263	deoxyribonucleotide biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6f65, PDBe:6f65, PDBj:6f65
PDBsum	6f65
PubMed	30689052
UniProt	Q5KW80

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