Structure of PDB 6f3h Chain A Binding Site BS01

Receptor Information
>6f3h Chain A (length=762) Species: 5478 (Nakaseomyces glabratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSFDPAELLRTSLNVGDIVLLKQCTSELTMCVNLPQSTTDPRYTFAKKD
GTLVYAMKNSVILRIPKPVLTRQLIVSFTLATFTKFAWTQLPIVLKKLEL
IHRYLQDSRGSKHVNFMSLVRIIKNLNIKEATDAIDAYVRKVIDESMSNK
SIDPTTLLATYWGVREQQQNNLWGSVYTNTALLSPTTVAVLPLKKAHLFY
QEVITRLESNDYQEIKAFAKLVNDKDYHSIAKRYDYIRTLLNDYAAGNIE
ENAVLTTIISKIFRHIDMYRDQDVTRSLCGKLLVEISPQSNSSNFILGNW
DLNIPKSGISSVEQKLYDTAMPTIVTDRYDFGDMPVFCIDSEDAHEINDG
ISIEELDGVRSRIHIHIADPAGLFPESFDYTKSGISDDVLRVSLKRAFTT
YLPDLVVPMLPKSFCNRADLGKHDRKTETISFSFELVNKEDGGLHVDYDT
FQVRLGIVSNFPKVTYDKVDSILNGDDNSLPSKQKKQLELLHTLATKLLH
KRIHDDNAVVFGDGFNKGLVSLSPDDELCIPTFYDQSQTKSTLLVSEFMI
LTNKLCAAFFQENKIPGVYRCYNGLNLGNQAKAQFELLKENIKLGKLPSL
KDITKISSQLSSSFYSPFPLPHKMIGNTAYLTVTSPMRRGPDLINHLQLH
RFLKKLPLCFKQEYLDQYVWSFQARADILKIFQRHSSTYWTLKHLEQSGK
THDVIVTSVPQNGTVNCLFPEYSYARGTLKLDPAMIPRIGDTIRHCKVES
IHPLDGILTLTH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6f3h Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Resolution2.703 Å
Binding residue
(original residue number in PDB)		T306 D469 H474 E475 N477 Y530 Y595 F640 Q667 S677 M680 I681 R701 S738 S742 S743 S744 H753 M755 Y761 T765 R769
Binding residue
(residue number reindexed from 1)		T180 D340 H345 E346 N348 Y401 Y466 F511 Q536 S546 M549 I550 R570 S607 S611 S612 S613 H622 M624 Y630 T634 R638
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
GO:0046872 metal ion binding
Biological Process
GO:0000957 mitochondrial RNA catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0045025 mitochondrial degradosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f3h, PDBe:6f3h, PDBj:6f3h
PDBsum6f3h
PubMed29311576
UniProtQ6FJE0

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