Structure of PDB 6f1d Chain A Binding Site BS01

Receptor Information
>6f1d Chain A (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPF
DIEDHPEVPCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTD
ESGDSRGWKLRYTTEII
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6f1d Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6f1d Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		E226 D236 D273 S275
Binding residue
(residue number reindexed from 1)		E53 D63 D100 S102
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.41: complement subcomponent C1r.
External links
PDB RCSB:6f1d, PDBe:6f1d, PDBj:6f1d
PDBsum6f1d
PubMed29311313
UniProtP00736|C1R_HUMAN Complement C1r subcomponent (Gene Name=C1R)

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