Structure of PDB 6ey7 Chain A Binding Site BS01

Receptor Information
>6ey7 Chain A (length=225) Species: 10360 (Human herpesvirus 5 strain AD169) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTRKASGTGVAAV
GAYRHQFLIYGLEHFFLRDLSESSEVAIAECAAHMIISVLSLHPYLDELR
IAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMG
RDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRS
DDLIIAVIMATYLCDDIHAIRFRVS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6ey7 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ey7 Structure-Driven Discovery of alpha , gamma-Diketoacid Inhibitors Against UL89 Herpesvirus Terminase.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D463 E534
Binding residue
(residue number reindexed from 1)		D35 E104
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Biological Process
GO:0051276 chromosome organization

View graph for
Biological Process
External links
PDB RCSB:6ey7, PDBe:6ey7, PDBj:6ey7
PDBsum6ey7
PubMed31458978
UniProtP16732|TRM3_HCMVA Tripartite terminase subunit 3 (Gene Name=TRM3)

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