Structure of PDB 6evo Chain A Binding Site BS01
Receptor Information
>6evo Chain A (length=95) Species:
9606
(Homo sapiens) [
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MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDY
LSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEE
Ligand information
>6evo Chain C (length=9) Species:
32630
(synthetic construct) [
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PPGPRGPPG
Receptor-Ligand Complex Structure
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PDB
6evo
Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif.
Resolution
1.55 Å
Binding residue
(original residue number in PDB)
R155 Y158 N159 D192 Y193 Y196 F199 R223 N227 Y230 F231
Binding residue
(residue number reindexed from 1)
R12 Y15 N16 D49 Y50 Y53 F56 R80 N84 Y87 F88
Enzymatic activity
Enzyme Commision number
1.14.11.2
: procollagen-proline 4-dioxygenase.
External links
PDB
RCSB:6evo
,
PDBe:6evo
,
PDBj:6evo
PDBsum
6evo
PubMed
30168208
UniProt
O15460
|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 (Gene Name=P4HA2)
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